Scott We run anywhere we are located including harbors/anchorages as long as there's no oil in the water and the water is not loaded with sand/silt. No issues whatsoever on this in the 4000 gallons. Just make sure you have a good sized pre-filter on it to get the bit chucks ;-) 80 gals a day is quite a bit for the 160 but no worries as you just turn your tanks quicker. If the PUR has all the latest mods it should handle that at least for a while. Maybe 12 hours of run time every other day. I have yet to find someone who has had a "fully automatic" watermaker that hasn't either had mucho issues or bypassed most of the automatic features. A simple one like you have run every other day and then shut down sure beats the phones calls, manual reading, waiting for parts and cursing when the fancy ones stops. We have but two valves to flip. One for the pressure and the other for the product water. If we wish to backflush or clean then there are more but for daily use just two. The location of the units should be where you can get to it easily....not hidden back in some upside down locker, IMHO. No mater which one you have it does require periodic service. If you can't do so it won't last long. Watermakers are not an install and forget type of equipment. The unfortunate part with the automatic ones is that a watermaker has saltwater under high pressure (~800 lbs). They also usually have many more connections in the water loop to allow all the various functions to work. ANY leak can produce a spray or drip which is death to the electronics. As always YMMV.... Dave & Nancy Swan Song Roughwater 58