Having only sailed that direction once, I can only offer one thought, we departed the San Blas in May, bound for the W side of Cuba. At times we had 2kts of current pushing us. I'd look at the currents in the basin to insure I was making the most favorable trip from a wind and current perspective. My sense is taking the E route (Mona Passage) would make the most sense going from N to S? Also, try to budget some time in the San Blas, they are like no other place on earth! Good luck! Scott Scott E. Bulger, Boatless in Seattle